Stock Based Compensation - Summary of Stock Awards Granted (Detail) - $ / shares	3 Months Ended
	Mar. 31, 2024		Mar. 31, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Grants, Stock options	316,378		1,030,349
Weighted Average Grant Date Fair Value, Stock options	$ 67.56		$ 72.8
Grants, Restricted stock units	1,161,985	[1]	1,075,911	[2]
Weighted Average Grant Date Fair Value, Restricted stock units	$ 128.58		$ 154.91
Restricted Stock Units [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Grants, Stock options	88,600		502,255

[1] (1) Included in restricted stock units (“RSUs”) for the three months ended March 31, 2024 are 88,600 shares with performance conditions, which are related to the achievement of certain financial performance goals, regulatory approval of certain of the Company's product candidates, and regulatory expansion of certain of the Company's commercial products. As of March 31, 2024, none of the performance conditions were probable of being achieved. If the performance milestones are achieved within the required time frame, the Company may recognize up to $14.3 million of stock-based compensation related to these grants. Stock options and the remaining RSUs granted during the three months ended March 31, 2024 have only service-based criteria and vest over four years.

[2] (2) Included in the RSUs for the three months ended March 31, 2023 are 502,255 shares with performance conditions (the “March 2023 PSUs”) which are related to regulatory approval of certain of the Company's product candidates and achievement of a certain financial performance target. The Company recorded stock-based compensation expense of $8.9 million associated with the March 2023 PSUs during the three months ended March 31, 2024, with no similar expense recorded during the three months ended March 31, 2023. Vesting of the March 2023 PSUs is contingent on the fulfillment of remaining service conditions.