As of
March 31, 2024

As of
December 31, 2023

(in thousands)

Product revenue related reserves

$

97,216

$

100,075

Accrued contract manufacturing costs

45,057

33,024

Accrued clinical and pre-clinical costs

36,078

34,669

Accrued employee compensation costs

32,112

78,732

Accrued professional fees

21,014

17,187

Accrued income taxes

18,292

13,766

Accrued fixed assets

11,587

3,231

Accrued royalties

11,206

12,070

Accrued research expenses

2,873

2,441

Accrued milestone and license expenses

2,000

11,375

Other

5,882

8,427

Total accrued expenses

$

283,317

$

314,997