Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2024	Dec. 31, 2023
Current assets:
Cash and cash equivalents	$ 427,290	$ 428,430
Short-term investments	963,453	1,247,820
Accounts receivable, net	378,806	400,327
Inventory	373,530	322,859
Manufacturing-related deposits and prepaids	238,821	102,181
Other current assets	82,965	77,714
Total current assets	2,464,865	2,579,331
Property and equipment, net	249,302	227,154
Right of use assets	126,269	129,952
Non-current inventory	207,542	191,368
Other non-current assets	176,407	136,771
Total assets	3,224,385	3,264,576
Current liabilities:
Accounts payable	91,536	164,918
Accrued expenses	283,317	314,997
Deferred revenue, current portion	112,000	50,416
Current portion of long-term debt	105,586	105,483
Other current liabilities	16,270	17,845
Total current liabilities	608,709	653,659
Long-term debt	1,133,660	1,132,515
Lease liabilities, net of current portion	140,102	140,965
Deferred revenue, net of current portion	325,000	437,000
Contingent consideration	48,200	38,100
Other non-current liabilities	7,522	3,000
Total liabilities	2,263,193	2,405,239
Commitments and contingencies (Note 14)
Stockholders’ equity:
Preferred stock, $0.0001 par value, 3,333,333 shares authorized; none issued and outstanding	0	0
Common stock, $0.0001 par value, 198,000,000 shares authorized; 94,490,157 and 93,731,831 issued and outstanding at March 31, 2024, and December 31, 2023, respectively	9	9
Additional paid-in capital	5,371,968	5,304,623
Accumulated other comprehensive (loss) income, net of tax	(691)	918
Accumulated deficit	(4,410,094)	(4,446,213)
Total stockholders’ equity	961,192	859,337
Total liabilities and stockholders’ equity	$ 3,224,385	$ 3,264,576