Accrued Expenses - Summary of Accrued Expenses (Detail) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Payables and Accruals [Abstract]
Product revenue related reserves	$ 85,678	$ 68,784
Accrued contract manufacturing costs	60,998	202,173
Accrued employee compensation costs	51,143	65,946
Accrued clinical and pre-clinical costs	40,930	28,884
Accrued income taxes	24,677	12,521
Accrued professional fees	24,050	12,061
Accrued royalties	10,501	8,636
Accrued property and equipment purchases	9,382	984
Accrued milestone and license costs	3,750	7,702
Accrued research costs	3,516	1,629
Other	7,725	9,676
Total accrued expenses	$ 322,350	$ 418,996