Condensed Consolidated Statements of Stockholders' Equity - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock [Member]	Additional Paid-In Capital [Member]	Accumulated Other Comprehensive (Loss) Income [Member]	Accumulated Deficit [Member]
Balance at Dec. 31, 2021	$ 928,009	$ 9	$ 4,134,768	$ (20)	$ (3,206,748)
Balance (in shares) at Dec. 31, 2021		87,127
Exercise of options for common stock	997		997
Exercise of options for common stock, shares		18
Vest of restricted stock units		289
Issuance of common stock under employee stock purchase plan	3,993		3,993
Issuance of common stock under employee stock purchase plan, shares		62
Stock-based compensation	29,198		29,198
Unrealized gains from available-for-sale securities, net of tax	(286)			(286)
Net Income (Loss)	(105,025)				(105,025)
Balance at Mar. 31, 2022	856,886	$ 9	4,168,956	(306)	(3,311,773)
Balance (in shares) at Mar. 31, 2022		87,496
Balance at Dec. 31, 2021	928,009	$ 9	4,134,768	(20)	(3,206,748)
Balance (in shares) at Dec. 31, 2021		87,127
Partial settlement of capped call share options for 2024 Notes	26,317
Purchase of capped call share options for 2027 Notes	127,305
Net Income (Loss)	(594,244)
Balance at Sep. 30, 2022	430,840	$ 9	4,235,028	(3,205)	(3,800,992)
Balance (in shares) at Sep. 30, 2022		87,766
Balance at Mar. 31, 2022	856,886	$ 9	4,168,956	(306)	(3,311,773)
Balance (in shares) at Mar. 31, 2022		87,496
Exercise of options for common stock	339		339
Exercise of options for common stock, shares		11
Vest of restricted stock units		28
Stock-based compensation	102,892		102,892
Unrealized gains from available-for-sale securities, net of tax	(2,179)			(2,179)
Net Income (Loss)	(231,481)				(231,481)
Balance at Jun. 30, 2022	726,457	$ 9	4,272,187	(2,485)	(3,543,254)
Balance (in shares) at Jun. 30, 2022		87,535
Exercise of options for common stock	9,934		9,934
Exercise of options for common stock, shares		144
Vest of restricted stock units		33
Partial settlement of capped call share options for 2024 Notes	26,317		26,317
Issuance of common stock under employee stock purchase plan	3,477		3,477
Issuance of common stock under employee stock purchase plan, shares		54
Stock-based compensation	50,418		50,418
Purchase of capped call share options for 2027 Notes	(127,305)		(127,305)
Unrealized gains from available-for-sale securities, net of tax	(720)			(720)
Net Income (Loss)	(257,738)				(257,738)
Balance at Sep. 30, 2022	430,840	$ 9	4,235,028	(3,205)	(3,800,992)
Balance (in shares) at Sep. 30, 2022		87,766
Balance at Dec. 31, 2022	384,950	$ 9	4,296,841	(1,664)	(3,910,236)
Balance (in shares) at Dec. 31, 2022		87,950
Exercise of options for common stock	22,808		22,808
Exercise of options for common stock, shares		267
Vest of restricted stock units		390
Issuance of common stock for exchange of 2024 Notes	693,377		693,377
Issuance of common stock for exchange of 2024 Notes, shares		4,456
Partial settlement of capped call share options for 2024 Notes	80,645		80,645
Issuance of common stock under employee stock purchase plan	5,229		5,229
Issuance of common stock under employee stock purchase plan, shares		77
Stock-based compensation	41,250		41,250
Unrealized gains from available-for-sale securities, net of tax	1,245			1,245
Net Income (Loss)	(516,755)				(516,755)
Balance at Mar. 31, 2023	712,749	$ 9	5,140,150	(419)	(4,426,991)
Balance (in shares) at Mar. 31, 2023		93,140
Balance at Dec. 31, 2022	384,950	$ 9	4,296,841	(1,664)	(3,910,236)
Balance (in shares) at Dec. 31, 2022		87,950
Partial settlement of capped call share options for 2024 Notes	80,645
Purchase of capped call share options for 2027 Notes	0
Net Income (Loss)	(581,632)
Balance at Sep. 30, 2023	764,357	$ 9	5,256,854	(638)	(4,491,868)
Balance (in shares) at Sep. 30, 2023		93,537
Balance at Mar. 31, 2023	712,749	$ 9	5,140,150	(419)	(4,426,991)
Balance (in shares) at Mar. 31, 2023		93,140
Exercise of options for common stock	5,861		5,861
Exercise of options for common stock, shares		80
Vest of restricted stock units		54
Stock-based compensation	47,377		47,377
Unrealized gains from available-for-sale securities, net of tax	(636)			(636)
Net Income (Loss)	(23,940)				(23,940)
Balance at Jun. 30, 2023	741,411	$ 9	5,193,388	(1,055)	(4,450,931)
Balance (in shares) at Jun. 30, 2023		93,274
Exercise of options for common stock	9,873		9,873
Exercise of options for common stock, shares		142
Vest of restricted stock units		45
Issuance of common stock under employee stock purchase plan	5,532		5,532
Issuance of common stock under employee stock purchase plan, shares		76
Stock-based compensation	48,061		48,061
Unrealized gains from available-for-sale securities, net of tax	417			417
Net Income (Loss)	(40,937)				(40,937)
Balance at Sep. 30, 2023	$ 764,357	$ 9	$ 5,256,854	$ (638)	$ (4,491,868)
Balance (in shares) at Sep. 30, 2023		93,537