Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents, Fair value	$ 541,932	$ 966,777
Short-term investments	1,191,610	1,022,597
Accounts receivable	318,855	214,628
Inventory	244,011	203,968
Other current assets	154,441	149,891
Total current assets	2,450,849	2,557,861
Property and equipment, net	212,367	180,037
Right of use assets	133,454	64,954
Non-current inventory	176,112	162,545
Other non-current assets	136,925	162,969
Total assets	3,109,707	3,128,366
Current liabilities:
Accounts payable	87,948	95,875
Accrued expenses	322,350	418,996
Deferred revenue, current portion	22,494	89,244
Other current liabilities	17,951	15,489
Total current liabilities	450,743	619,604
Long-term debt	1,236,755	1,544,292
Lease liabilities, net of current portion	134,752	57,578
Deferred revenue, net of current portion	485,000	485,000
Contingent consideration	38,100	36,900
Other non-current liabilities	0	42
Total liabilities	2,345,350	2,743,416
Commitments and contingencies (Note 16)
Stockholders’ equity:
Preferred stock, $0.0001 par value, 3,333,333 shares authorized; none issued and outstanding	0	0
Common stock, $0.0001 par value, 198,000,000 shares authorized; 93,537,355 and 87,950,117 issued and outstanding at September 30, 2023, and December 31, 2022, respectively	9	9
Additional paid-in capital	5,256,854	4,296,841
Accumulated other comprehensive loss, net of tax	(638)	(1,664)
Accumulated deficit	(4,491,868)	(3,910,236)
Total stockholders’ equity	764,357	384,950
Total liabilities and stockholders’ equity	$ 3,109,707	$ 3,128,366