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Summary of Stock Awards Granted (Detail) - $ / shares
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Grants, Stock options 54,575 207,583 1,084,924 1,499,120
Weighted Average Grant Date Fair Value, Stock options $ 66.82 $ 43.4 $ 72.5 $ 46.49
Grants, Restricted stock units [1] 33,752 147,075 1,109,663 859,510
Weighted Average Grant Date Fair Value, Restricted stock units [1] $ 121.27 $ 72.99 $ 153.89 $ 78.78
Restricted Stock Units [Member]        
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]        
Grants, Stock options 502,225 38,500 502,225 38,500
Grants, Restricted stock units 394,975   394,975  
[1] Included in restricted stock units (“RSUs”) for the three and six months ended June 30, 2023 and 2022 are 502,225 and 38,500 shares, respectively, with performance conditions (“PSUs”) which are related to regulatory approval of certain of the Company's product candidates. As a result of the regulatory approval of ELEVIDYS in June 2023, the Compensation Committee of the Company's Board of Directors determined that one of the performance conditions was met, resulting in the recognition of stock-based compensation expense of $7.4 million associated with 394,975 PSUs with performance conditions during the three and six months ended June 30, 2023. Vesting of the 394,975 PSUs with performance conditions achieved is contingent on the fulfillment of remaining service conditions. The remaining expense associated with the 394,975 PSUs with performance conditions achieved is $54.2 million and will be recognized over approximately the next 1.7 years. If the performance milestones are met within the required time frame for the remaining PSUs, the Company may recognize up to $22.4

million of stock-based compensation expense. Stock options and the remaining RSUs granted during the periods presented in the table have only service-based criteria and vest over four years.