Accrued Expenses - Summary of Accrued Expenses (Detail) - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Payables and Accruals [Abstract]
Accrued contract manufacturing costs	$ 82,734	$ 202,173
Product revenue related reserves	80,424	68,784
Accrued employee compensation costs	44,906	65,946
Accrued clinical and pre-clinical costs	39,786	28,884
Accrued professional fees	19,984	12,061
Accrued income taxes	20,815	12,521
Accrued milestone and license costs	11,200	7,702
Accrued royalties	8,583	8,636
Accrued fixed assets	6,027	984
Accrued research costs	2,627	1,629
Other	9,791	9,676
Total accrued expenses	$ 326,877	$ 418,996