Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 851,929	$ 966,777
Short-term investments	1,008,786	1,022,597
Accounts receivable	236,808	214,628
Inventory	226,876	203,968
Other current assets	148,215	149,891
Total current assets	2,472,614	2,557,861
Property and equipment, net	188,874	180,037
Right of use assets	134,728	64,954
Non-current inventory	166,635	162,545
Other non-current assets	163,039	162,969
Total assets	3,125,890	3,128,366
Current liabilities:
Accounts payable	109,796	95,875
Accrued expenses	326,877	418,996
Deferred revenue, current portion	44,989	89,244
Other current liabilities	16,992	15,489
Total current liabilities	498,654	619,604
Long-term debt	1,235,517	1,544,292
Lease liabilities, net of current portion	129,170	57,578
Deferred revenue, net of current portion	485,000	485,000
Contingent consideration	36,100	36,900
Other non-current liabilities	38	42
Total liabilities	2,384,479	2,743,416
Commitments and contingencies (Note 16)
Stockholders’ equity:
Preferred stock, $0.0001 par value, 3,333,333 shares authorized; none issued and outstanding	0	0
Common stock, $0.0001 par value, 198,000,000 shares authorized; 93,273,541 and 87,950,117 issued and outstanding at June 30, 2023, and December 31, 2022, respectively	9	9
Additional paid-in capital	5,193,388	4,296,841
Accumulated other comprehensive loss, net of tax	(1,055)	(1,664)
Accumulated deficit	(4,450,931)	(3,910,236)
Total stockholders’ equity	741,411	384,950
Total liabilities and stockholders’ equity	$ 3,125,890	$ 3,128,366