Accrued Expenses - Summary of Accrued Expenses (Detail) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Payables and Accruals [Abstract]
Accrued contract manufacturing costs	$ 155,609	$ 202,173
Product revenue related reserves	68,692	68,784
Accrued clinical and pre-clinical costs	35,968	28,884
Accrued employee compensation costs	27,849	65,946
Accrued professional fees	18,972	12,061
Accrued income taxes	16,092	12,521
Accrued royalties	8,383	8,636
Accrued fixed assets	7,451	984
Accrued research costs	2,177	1,629
Other	4,361	17,378
Total accrued expenses	$ 345,554	$ 418,996