Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 871,668	$ 966,777
Short-term investments	1,010,429	1,022,597
Accounts receivable	223,836	214,628
Inventory	202,675	203,968
Other current assets	179,769	149,891
Total current assets	2,488,377	2,557,861
Property and equipment, net	182,862	180,037
Right of use assets	62,016	64,954
Non-current inventory	164,144	162,545
Other non-current assets	162,387	162,969
Total assets	3,059,786	3,128,366
Current liabilities:
Accounts payable	106,710	95,875
Accrued expenses	345,554	418,996
Deferred revenue, current portion	67,239	89,244
Other current liabilities	17,381	15,489
Total current liabilities	536,884	619,604
Long-term debt	1,234,284	1,544,292
Lease liabilities, net of current portion	53,931	57,578
Deferred revenue, net of current portion	485,000	485,000
Contingent consideration	36,900	36,900
Other non-current liabilities	38	42
Total liabilities	2,347,037	2,743,416
Commitments and contingencies (Note 13)
Stockholders’ equity:
Preferred stock, $0.0001 par value, 3,333,333 shares authorized; none issued and outstanding	0	0
Common stock, $0.0001 par value, 198,000,000 shares authorized; 87,535,299 and 87,126,974 issued and outstanding at June 30, 2022, and December 31, 2021, respectively	9	9
Additional paid-in capital	5,140,150	4,296,841
Accumulated other comprehensive loss, net of tax	(419)	(1,664)
Accumulated deficit	(4,426,991)	(3,910,236)
Total stockholders’ equity	712,749	384,950		$ 928,009
Total liabilities and stockholders’ equity	$ 3,059,786	$ 3,128,366