Income Taxes - Additional Information (Detail) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Income Taxes [Line Items]
current state tax expense	$ 13,193,000	$ (40,000)	$ 624,000
Net change in valuation allowance for deferred tax assets	139,600,000	66,500,000
Net operating loss carried forwards	241,826,000	330,392,000
Accrual for interest or penalties	0	0
Recognized interest and/or penalties	$ 0	$ 0
Minimum [Member]
Income Taxes [Line Items]
Operating loss carryforwards, ending of expiration year	2023
Maximum [Member]
Income Taxes [Line Items]
Operating loss carryforwards, ending of expiration year	2041
Federal [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	$ 925,700,000
Net operating loss carryforwards subject to expiration	229,800,000
Net operating loss carried forwards	695,900,000
State [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	616,200,000
Net operating loss carryforwards subject to expiration	572,000,000.0
Net operating loss carried forwards	44,200,000
Foreign [Member]
Income Taxes [Line Items]
Net operating loss carryforwards	$ 15,300,000
Research and Development Credits [Member]
Income Taxes [Line Items]
Research and development credits carryforward, Description	These federal and state research and development credits begin to expire between 2023 and 2042 and between 2023 and 2037, respectively.
Research and Development Credits [Member] | Federal [Member]
Income Taxes [Line Items]
Research and development credits carryforward, Amount	$ 180,100,000
Research and Development Credits [Member] | State [Member]
Income Taxes [Line Items]
Research and development credits carryforward, Amount	$ 102,400,000