Summary of Stock Option Activity (Detail) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2022 USD ($) $ / shares shares
Stock Option Shares
Grants outstanding at beginning of the period | shares	8,196,921
Granted | shares	1,777,370
Exercised | shares	(318,258)
Cancelled and forfeited | shares	(525,893)
Grants outstanding at end of the period | shares	9,130,140
Grants exercisable at end of the period | shares	4,692,578
Grants vested and expected to vest at end of the period | shares	8,696,519
Weighted Average Exercise Price
Grants outstanding at beginning of the period | $ / shares	$ 69.39
Granted | $ / shares	84.70
Exercised | $ / shares	70.25
Cancelled and forfeited | $ / shares	109.31
Grants outstanding at end of the period | $ / shares	70.04
Grants exercisable at end of the period | $ / shares	70.27
Grants vested and expected to vest at end of the period | $ / shares	$ 69.05
Aggregate Intrinsic Value
Outstanding at end of year | $	$ 557,927
Exercisable at end of year | $	289,473
Vested and expected to vest | $	$ 540,503
Weighted Average Remaining Contractual Life (Years)
Outstanding at end of year	6 years 1 month 6 days
Exercisable at end of year	5 years 2 months 12 days
Vested and expected to vest	6 years