Other (Loss) Income, Net - Summary of Other Loss (Detail) - USD ($) $ in Thousands		3 Months Ended		9 Months Ended
		Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Nonoperating Income (Expense) [Abstract]
Interest expense		$ (14,736)	$ (15,995)	$ (46,560)	$ (47,477)
Interest income		4,780	148	7,362	259
Gain on contingent consideration, net	[1]	6,700	7,200	6,700	7,200
Loss on debt extinguishment		(125,441)	0	(125,441)	0
Impairment of equity investment		0	(4,488)	0	(4,488)
Gain from sale of Priority Review Voucher		0	0	0	102,000
Other expense, net		3,634	(314)	(1,350)	(656)
Total other (loss) income, net		$ (125,063)	$ (13,449)	$ (159,289)	$ 56,838

[1] The gain on contingent consideration, net is related to the fair value adjustment of the regulatory-related contingent payments that are accounted for as derivatives. Please see Note 4, Fair Value Measurements for further details.