ACCRUED EXPENSES

9 Months Ended

Sep. 30, 2022

Payables and Accruals [Abstract]

ACCRUED EXPENSES

9. ACCRUED EXPENSES

The following table summarizes the Company’s accrued expenses for each of the periods indicated:

	As of September 30, 2022		As of December 31, 2021
	(in thousands)
Accrued contract manufacturing costs	$	190,343	$	104,311
Product revenue related reserves		67,942		62,145
Accrued employee compensation costs		42,689		48,299
Accrued clinical and pre-clinical costs		31,794		25,955
Accrued professional fees		13,888		9,381
Accrued royalties		7,862		11,965
Accrued income taxes		4,095		216
Accrued interest expense		2,935		1,045
Accrued collaboration cost sharing		1,868		2,887
Accrued sponsored research agreements		1,237		3,377
Other		4,345		2,116
Total accrued expenses	$	368,998	$	271,697