Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 868,565	$ 2,115,869
Short-term investments	1,059,454	0
Accounts receivable	203,854	152,990
Inventory	208,095	186,212
Other current assets	129,332	149,028
Total current assets	2,469,300	2,604,099
Property and equipment, net	183,292	191,156
Intangible assets, net	13,062	14,239
Right of use assets	46,999	45,531
Other non-current assets	284,200	292,949
Total assets	2,996,853	3,147,974
Current liabilities:
Accounts payable	56,207	76,741
Accrued expenses	383,699	271,697
Deferred revenue, current portion	89,244	89,244
Other current liabilities	16,416	15,051
Total current liabilities	545,566	452,733
Long-term debt	1,100,873	1,096,876
Lease liabilities, net of current portion	39,368	41,512
Deferred revenue, net of current portion	529,989	574,244
Contingent consideration	43,600	43,600
Other non-current liabilities	11,000	11,000
Total liabilities	2,270,396	2,219,965
Commitments and contingencies (Note 13)
Stockholders’ equity:
Preferred stock, $0.0001 par value, 3,333,333 shares authorized; none issued and outstanding	0	0
Common stock, $0.0001 par value, 198,000,000 shares authorized; 87,535,299 and 87,126,974 issued and outstanding at June 30, 2022, and December 31, 2021, respectively	9	9
Additional paid-in capital	4,272,187	4,134,768
Accumulated other comprehensive loss, net of tax	(2,485)	(20)
Accumulated deficit	(3,543,254)	(3,206,748)
Total stockholders’ equity	726,457	928,009
Total liabilities and stockholders’ equity	$ 2,996,853	$ 3,147,974