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Summary of Aggregate Non-Cancelable Contractual Obligations Arising from Manufacturing Obligations (Detail) - Manufacturing Commitments Agreement [Member] - Catalent and Thermo [Member]
$ in Thousands
Mar. 31, 2022
USD ($)
Commitments And Contingencies [Line Items]  
2022 (April - December) $ 651,791
2023 248,256
2024 136,740
2025 100,296
2026 54,720
Thereafter 109,440
Total manufacturing commitments $ 1,301,243 [1]
[1] Total manufacturing commitments includes the Catalent Inc. manufacturing and supply agreement, for which the Company has right of use assets and lease liabilities recorded on the unaudited condensed consolidated balance sheets as of March 31, 2022. For more information, please read Note 21, Commitments and Contingencies of the Company’s Annual Report on Form 10-K for the year ended December 31, 2021.