Summary of Other Current Assets (Detail) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Prepaid Expense and Other Assets, Current [Abstract]
Manufacturing-related deposits and prepaids	$ 86,431	$ 93,656
Collaboration receivable	17,722	18,647
Prepaid clinical and pre-clinical expenses	9,975	12,667
Prepaid maintenance services	9,312	8,452
Prepaid insurance	3,331	5,282
Prepaid research expenses	2,772	3,082
Prepaid commercial expenses	2,119	831
Interest receivable	1,285	8
Prepaid income tax	376	1,100
Other	7,008	5,303
Total other current assets	$ 140,331	$ 149,028