Summary of Other Income (Loss) (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021		Dec. 31, 2020		Dec. 31, 2019
Nonoperating Income (Expense) [Abstract]
Interest expense	$ (63,525)		$ (59,947)		$ (30,669)
Interest income	354		2,970		7,238
Amortization of investment discount	157		4,489		15,350
Gain from sale of Priority Review Voucher	102,000		108,069
Gain (loss) on contingent consideration, net	7,200	[1]	(45,000)	[1]
Impairment of equity investment	(4,488)
Other expense	(936)		517		(236)
Total other income (loss)	$ 40,762		$ 11,098		$ (8,317)

[1] The gain (loss) on contingent consideration, net is related to the fair value adjustment of the regulatory-related contingent payments that are accounted for as derivatives. Please see Note 5. Fair Value Measurements for further details.