Summary of Other Current Assets (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Prepaid Expense and Other Assets, Current [Abstract]
Manufacturing-related deposits and prepaids	$ 93,656	$ 134,430
Collaboration receivable	18,647	34,184
Prepaid clinical and pre-clinical expenses	12,667	16,224
Prepaid maintenance services	8,452	6,411
Prepaid research expenses	3,082	5,854
Prepaid income tax	1,100	4,939
Prepaid insurance	5,282	4,158
Leasehold improvement receivable	0	3,059
Other	6,142	4,065
Total other current assets	$ 149,028	$ 213,324