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Gain from Sale of Priority Review Voucher - Additional Information (Detail) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
F D A    
Gain From Sale Of Intangible Asset [Line Items]    
Proceeds from sale of rare pediatric disease priority review voucher, Net of commission $ 102.0 $ 108.1