DELCATH SYSTEMS, INC.

EXHIBIT 32.2

Certification Pursuant to

18 U.S.C. Section 1350,

as Adopted Pursuant to

Section 906 of the Sarbanes –Oxley Act of 2002

In connection with the Quarterly Report of DELCATH SYSTEMS, INC. (the “Company”) on Form 10-Q for the fiscal quarter ended June 6, 2014, as filed with the Securities and Exchange Commission on the date hereof (the “Report”), I, Jennifer K. Simpson, the Interim Co-President and Co-Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. § 1350, as adopted pursuant to § 906 of the Sarbanes-Oxley Act of 2002, that, to my knowledge:

(1)       The Report fully complies with the requirements of section 13(a) or 15(d), as applicable, of the Securities Exchange Act of 1934, as amended; and

(2)        The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

August 6, 2014
	/s/Jennifer K. Simpson
	Jennifer K. Simpson
	Interim Co-President and Co-Chief Executive Officer,
	Global Head of Business Operations
	(Co-Principal executive officer)