PORTFOLIO OF INVESTMENTS – as of June 30, 2022 (Unaudited)

Loomis Sayles Small Cap Growth Fund

Shares		Description	Value (†)
	Common Stocks – 95.9% of Net Assets
		Air Freight & Logistics – 0.6%
	171,916	HUB Group, Inc., Class A(a)	$	12,195,721
		Auto Components – 3.9%
	278,383	Dorman Products, Inc.(a)		30,541,399
	155,139	Fox Factory Holding Corp.(a)		12,494,895
	335,213	Gentherm, Inc.(a)		20,920,643
	289,303	Patrick Industries, Inc.		14,997,468
				78,954,405
		Banks – 2.8%
	435,918	Ameris Bancorp		17,515,185
	897,640	Bancorp, Inc. (The)(a)		17,521,933
	322,148	Lakeland Financial Corp.		21,397,070
				56,434,188
		Beverages – 0.9%
	1,284,241	Primo Water Corp.		17,183,145
		Biotechnology – 5.8%
	188,564	Blueprint Medicines Corp.(a)		9,524,368
	820,450	Halozyme Therapeutics, Inc.(a)		36,099,800
	593,019	Inhibrx, Inc.(a)		6,730,766
	727,148	Insmed, Inc.(a)		14,339,358
	548,927	PTC Therapeutics, Inc.(a)		21,990,016
	468,907	Vericel Corp.(a)		11,807,078
	623,503	Xencor, Inc.(a)		17,065,277
				117,556,663
		Building Products – 3.3%
	350,237	Advanced Drainage Systems, Inc.		31,545,846
	202,500	Simpson Manufacturing Co., Inc.		20,373,525
	222,590	UFP Industries, Inc.		15,167,283
				67,086,654
		Capital Markets – 3.6%
	501,677	Focus Financial Partners, Inc., Class A(a)		17,087,119
	368,419	Hamilton Lane, Inc., Class A		24,750,388
	422,015	PJT Partners, Inc., Class A		29,659,214
				71,496,721
		Commercial Services & Supplies – 2.8%
	541,741	Casella Waste Systems, Inc., Class A(a)		39,373,736
	584,891	Driven Brands Holdings, Inc.(a)		16,107,898
				55,481,634
		Communications Equipment – 1.4%
	483,168	Calix, Inc.(a)		16,495,355
	530,522	Radware Ltd.(a)		11,496,412
				27,991,767

Shares		Description	Value (†)
	Common Stocks – continued
		Construction & Engineering – 1.6%
	971,563	WillScot Mobile Mini Holdings Corp.(a)	$	31,498,072
		Electronic Equipment, Instruments & Components – 2.9%
	232,548	Advanced Energy Industries, Inc.		16,971,353
	205,757	Itron, Inc.(a)		10,170,568
	563,407	nLight, Inc.(a)		5,758,020
	206,419	Novanta, Inc.(a)		25,032,432
				57,932,373
		Energy Equipment & Services – 2.6%
	673,475	Cactus, Inc., Class A		27,120,838
	477,897	Noble Corp.(a)		12,114,689
	649,415	Weatherford International PLC(a)		13,748,116
				52,983,643
		Food Products – 2.1%
	504,448	Hostess Brands, Inc.(a)		10,699,342
	814,789	Simply Good Foods Co. (The)(a)		30,774,581
				41,473,923
		Health Care Equipment & Supplies – 8.0%
	526,282	AtriCure, Inc.(a)		21,503,883
	583,657	Axonics, Inc.(a)		33,075,842
	235,161	CONMED Corp.		22,519,017
	187,734	Cutera, Inc.(a)		7,040,025
	210,394	LivaNova PLC(a)		13,143,313
	485,672	Merit Medical Systems, Inc.(a)		26,357,419
	467,310	NuVasive, Inc.(a)		22,972,960
	197,274	STAAR Surgical Co.(a)		13,992,645
				160,605,104
		Health Care Providers & Services – 4.6%
	361,124	Acadia Healthcare Co., Inc.(a)		24,422,816
	306,787	Ensign Group, Inc. (The)		22,539,641
	113,334	ModivCare, Inc.(a)		9,576,723
	1,280,320	Option Care Health, Inc.(a)		35,580,093
				92,119,273
		Health Care Technology – 3.7%
	1,437,530	Evolent Health, Inc., Class A(a)		44,146,546
	168,532	Inspire Medical Systems, Inc.(a)		30,785,741
				74,932,287
		Hotels, Restaurants & Leisure – 2.3%
	916,149	Life Time Group Holdings, Inc.(a)		11,799,999
	210,992	Papa John’s International, Inc.		17,622,052
	229,173	Texas Roadhouse, Inc.		16,775,464
				46,197,515
		Household Durables – 0.8%
	186,713	Installed Building Products, Inc.		15,527,053

Shares		Description	Value (†)
	Common Stocks – continued
		Insurance – 1.5%
	624,265	BRP Group, Inc., Class A(a)	$	15,076,000
	63,145	Kinsale Capital Group, Inc.		14,500,618
				29,576,618
		Interactive Media & Services – 0.7%
	623,177	CarGurus, Inc.(a)		13,392,074
		Internet & Direct Marketing Retail – 0.9%
	329,264	Shutterstock, Inc.		18,870,120
		IT Services – 3.8%
	693,072	EVERTEC, Inc.		25,560,496
	177,242	Perficient, Inc.(a)		16,251,319
	469,777	WNS Holdings Ltd., ADR(a)		35,064,155
				76,875,970
		Leisure Products – 2.3%
	790,117	Callaway Golf Co.(a)		16,118,387
	337,826	Malibu Boats, Inc., Class A(a)		17,806,809
	270,983	YETI Holdings, Inc.(a)		11,725,434
				45,650,630
		Life Sciences Tools & Services – 1.0%
	138,678	Medpace Holdings, Inc.(a)		20,755,936
		Machinery – 4.2%
	348,617	Albany International Corp., Class A		27,467,533
	344,032	Helios Technologies, Inc.		22,792,120
	138,484	RBC Bearings, Inc.(a)		25,612,616
	506,619	Shyft Group, Inc. (The)		9,418,047
				85,290,316
		Media – 1.3%
	400,971	TechTarget, Inc.(a)		26,351,814
		Personal Products – 2.1%
	421,038	BellRing Brands, Inc.(a)		10,479,636
	725,406	elf Beauty, Inc.(a)		22,255,456
	143,056	Inter Parfums, Inc.		10,451,671
				43,186,763
		Pharmaceuticals – 2.3%
	456,277	Pacira BioSciences, Inc.(a)		26,600,949
	694,596	Supernus Pharmaceuticals, Inc.(a)		20,087,716
				46,688,665
		Professional Services – 3.7%
	120,411	FTI Consulting, Inc.(a)		21,776,329
	170,636	Huron Consulting Group, Inc.(a)		11,089,634
	873,796	KBR, Inc.		42,282,988
				75,148,951

Shares		Description	Value (†)
	Common Stocks – continued
		Semiconductors & Semiconductor Equipment – 4.9%
	566,067	MACOM Technology Solutions Holdings, Inc.(a)	$	26,095,689
	557,014	MaxLinear, Inc.(a)		18,927,336
	1,235,394	Rambus, Inc.(a)		26,548,617
	195,891	Silicon Laboratories, Inc.(a)		27,467,836
				99,039,478
		Software – 6.7%
	171,308	Blackline, Inc.(a)		11,409,113
	539,402	Box, Inc., Class A(a)		13,560,566
	373,862	Envestnet, Inc.(a)		19,728,698
	338,153	Q2 Holdings, Inc.(a)		13,042,561
	444,084	Rapid7, Inc.(a)		29,664,811
	545,660	Tenable Holdings, Inc.(a)		24,778,421
	742,064	Varonis Systems, Inc.(a)		21,757,316
				133,941,486
		Specialty Retail – 0.8%
	222,859	Boot Barn Holdings, Inc.(a)		15,357,214
		Technology Hardware, Storage & Peripherals – 1.5%
	1,174,825	Pure Storage, Inc., Class A(a)		30,204,751
		Textiles, Apparel & Luxury Goods – 1.7%
	225,145	Columbia Sportswear Co.		16,115,879
	215,891	Oxford Industries, Inc.		19,158,167
				35,274,046
		Trading Companies & Distributors – 2.8%
	180,770	Applied Industrial Technologies, Inc.		17,384,651
	248,552	McGrath RentCorp		18,889,952
	164,613	SiteOne Landscape Supply, Inc.(a)		19,567,547
				55,842,150
		Total Common Stocks (Identified Cost $1,900,816,256)		1,929,097,123
Principal          Amount
	Short-Term Investments – 3.8%
$	75,111,132	Tri-Party Repurchase Agreement with Fixed Income Clearing Corporation, dated 6/30/2022 at 0.350% to be repurchased at $75,111,862 on 7/01/2022 collateralized by $76,267,800 U.S. Treasury Note, 3.250% due 6/30/2027 valued at $76,613,370 including accrued interest(b) (Identified Cost $75,111,132)		75,111,132
		Total Investments – 99.7% (Identified Cost $1,975,927,388)		2,004,208,255
		Other assets less liabilities – 0.3%		6,981,458
		Net Assets – 100.0%	$	2,011,189,713

(†) Fund securities and other investments are valued at market value based on market quotations obtained or determined by independent pricing services recommended by the adviser and approved by the Board of Trustees. Fund securities and other investments for which market quotations are not readily available are valued at fair value as determined in good faith by the adviser pursuant to procedures approved by the Board of Trustees, as described below. Market value is determined as follows:

Listed equity securities (including shares of closed-end investment companies and exchange-traded funds) are valued at the last sale price quoted on the exchange where they are traded most extensively or, if there is no reported sale during the day, the closing bid quotation as reported by an independent pricing service. Securities traded on the NASDAQ Global Select Market, NASDAQ Global Market and NASDAQ Capital Market are valued at the NASDAQ Official Closing Price (“NOCP”), or if lacking an NOCP, at the most recent bid quotations on the applicable NASDAQ Market. Unlisted equity securities (except unlisted preferred equity securities) are valued at the last sale price quoted in the market where they are traded most extensively or, if there is no reported sale during the day, the closing bid quotation as reported by an independent pricing service. If there is no last sale price or closing bid quotation available, unlisted equity securities will be valued using evaluated bids furnished by an independent pricing service, if available.

In some foreign markets, an official close price and a last sale price may be available from the foreign exchange or market. In those cases, the official close price is used.

Debt securities and unlisted preferred equity securities are valued based on evaluated bids furnished to the Fund by an independent pricing service or bid prices obtained from broker-dealers.

Broker-dealer bid prices may be used to value debt and unlisted equity securities where an independent pricing service is unable to price a security or where an independent pricing service does not provide a reliable price for the security.

Fund securities and other investments for which market quotations are not readily available are valued at fair value as determined in good faith by the adviser pursuant to procedures approved by the Board of Trustees. The Fund may also value securities and other investments at fair value in other circumstances such as when extraordinary events occur after the close of a foreign market but prior to the close of the New York Stock Exchange. This may include situations relating to a single issuer (such as a declaration of bankruptcy or a delisting of the issuer’s security from the primary market on which it has traded) as well as events affecting the securities markets in general (such as market disruptions or closings and significant fluctuations in U.S. and/or foreign markets). When fair valuing its securities or other investments, the Fund may, among other things, use modeling tools or other processes that may take into account factors such as securities or other market activity and/or significant events that occur after the close of the foreign market and before the time the Fund’s net asset value (“NAV”) is calculated. Fair value pricing may require subjective determinations about the value of a security, and fair values used to determine the Fund’s NAV may differ from quoted or published prices, or from prices that are used by others, for the same securities. In addition, the use of fair value pricing may not always result in adjustments to the prices of securities held by the Fund.

The books and records of the Fund are maintained in U.S. dollars. The values of securities, currencies and other assets and liabilities denominated in currencies other than U.S. dollars are translated into U.S. dollars based upon foreign exchange rates prevailing at the end of the period.

(a) Non-income producing security.

(b) The Fund may enter into repurchase agreements, under the terms of a Master Repurchase Agreement, under which the Fund acquires securities as collateral and agrees to resell the securities at an agreed upon time and at an agreed upon price. It is the Fund’s policy that the market value of the collateral for repurchase agreements be at least equal to 102% of the repurchase price, including interest. Certain repurchase agreements are tri-party arrangements whereby the collateral is held in a segregated account for the benefit of the Fund and on behalf of the counterparty. Repurchase agreements could involve certain risks in the event of default or insolvency of the counterparty, including possible delays or restrictions upon the Fund’s ability to dispose of the underlying securities. As of June 30, 2022, the Fund had an investment in a repurchase agreement for which the value of the related collateral exceeded the value of the repurchase agreement.

ADR An American Depositary Receipt is a certificate issued by a custodian bank representing the right to receive securities of the foreign issuer described. The values of ADRs may be significantly influenced by trading on exchanges not located in the United States.

Fair Value Measurements

In accordance with accounting standards related to fair value measurements and disclosures, the Fund has categorized the inputs utilized in determining the value of the Fund’s assets or liabilities. These inputs are summarized in the three broad levels listed below:

• Level 1 — quoted prices in active markets for identical assets or liabilities;

• Level 2 — prices determined using other significant inputs that are observable either directly, or indirectly through corroboration with observable market data (which could include quoted prices for similar assets or liabilities, interest rates, credit risk, etc.); and

• Level 3 — prices determined using significant unobservable inputs when quoted prices or observable inputs are unavailable such as when there is little or no market activity for an asset or liability (unobservable inputs reflect the Fund’s own assumptions in determining the fair value of assets or liabilities and would be based on the best information available).

The inputs or methodology used for valuing securities are not necessarily an indication of the risk associated with investing in those securities.

The following is a summary of the inputs used to value the Fund’s investments as of June 30, 2022, at value:

Asset Valuation Inputs

Description	Level 1		Level 2		Level 3		Total
Common Stocks*	$	1,929,097,123	$	—	$	—	$	1,929,097,123
Short-Term Investments		—		75,111,132		—		75,111,132
Total	$	1,929,097,123	$	75,111,132	$	—	$	2,004,208,255

* Details of the major categories of the Fund’s investments are reflected within the Portfolio of Investments.

Industry Summary at June 30, 2022 (Unaudited)
Health Care Equipment & Supplies	8.0	%
Software	6.7
Biotechnology	5.8
Semiconductors & Semiconductor Equipment	4.9
Health Care Providers & Services	4.6
Machinery	4.2
Auto Components	3.9
IT Services	3.8
Professional Services	3.7
Health Care Technology	3.7
Capital Markets	3.6
Building Products	3.3
Electronic Equipment, Instruments & Components	2.9
Banks	2.8
Trading Companies & Distributors	2.8
Commercial Services & Supplies	2.8
Energy Equipment & Services	2.6
Pharmaceuticals	2.3
Hotels, Restaurants & Leisure	2.3
Leisure Products	2.3
Personal Products	2.1
Food Products	2.1
Other Investments, less than 2% each	14.7
Short-Term Investments	3.8
Total Investments	99.7
Other assets less liabilities	0.3
Net Assets	100.0	%