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Property, Plant, and Equipment (Tables)
12 Months Ended
Dec. 31, 2023
Property, Plant and Equipment [Abstract]  
Schedule of property, plant and equipment The estimated useful lives of property, plant, and equipment are as follows:
Building and improvements
10–50 years
Laboratory and other equipment
3–10 years
Furniture and fixtures
5 years
Property, plant, and equipment, net consists of the following:
As of December 31,
(In millions)20232022
Building and improvements$2,423.1 $2,270.0 
Leasehold improvements133.9 114.3 
Laboratory equipment1,384.5 1,315.3 
Computer equipment and software389.7 337.4 
Furniture, office equipment, and other
165.9 150.2 
Land283.1 264.5 
Construction in progress1,345.0 980.5 
6,125.2 5,432.2 
Accumulated depreciation and amortization
(1,978.8)(1,669.2)
$4,146.4 $3,763.0