Collaboration, License, and Other Agreements - Amounts Recognized in Statement of Operations with Roche (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
Disaggregation of Revenue [Line Items]
Revenues	$ 3,362.7	$ 2,936.2	$ 9,682.9	$ 8,758.5
Ronapreve | Roche Collaboration Agreement | Collaboration revenue
Disaggregation of Revenue [Line Items]
Revenues	0.0	6.4	222.2	230.9
Other | Roche Collaboration Agreement | Collaboration revenue
Disaggregation of Revenue [Line Items]
Revenues	$ (5.7)	$ 0.0	$ (9.5)	$ 0.0