XML 31 R19.htm IDEA: XBRL DOCUMENT v3.23.2
Insider Trading Arrangements
 3 Months Ended 6 Months Ended
Jun. 30, 2023
shares
Jun. 30, 2023
shares
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement  
As disclosed in the table below, during the three months ended June 30, 2023, certain of our directors and/or executive officers adopted plans for trading arrangements intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) of the Exchange Act.
NamePositionDate of Plan Adoption
Scheduled End Date of Trading Arrangement(a)
Total Number of Securities to Be Sold Under the Plan
Bonnie L. Bassler, Ph.D.Director5/11/20237/31/20243,969 
Andrew J. Murphy, Ph.D.Executive Vice President, Research5/9/202312/31/202480,000 
Huda Y. Zoghbi, M.D.Director5/5/20232/10/20242,117 
(a) In each case, the trading arrangement may expire on an earlier date if and when all transactions under the arrangement are completed.
Non-Rule 10b5-1 Arrangement Adopted false  
Rule 10b5-1 Arrangement Terminated false  
Non-Rule 10b5-1 Arrangement Terminated false  
Bonnie L. Bassler, Ph.D. [Member]    
Trading Arrangements, by Individual    
Name Bonnie L. Bassler, Ph.D.  
Title Director  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 5/11/2023  
Arrangement Duration 447 days  
Aggregate Available 3,969 3,969
Andrew J. Murphy, Ph.D. [Member]    
Trading Arrangements, by Individual    
Name Andrew J. Murphy, Ph.D.  
Title Executive Vice President, Research  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 5/9/2023  
Arrangement Duration 602 days  
Aggregate Available 80,000 80,000
Huda Y. Zoghbi, M.D. [Member]    
Trading Arrangements, by Individual    
Name Huda Y. Zoghbi, M.D.  
Title Director  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 5/5/2023  
Arrangement Duration 281 days  
Aggregate Available 2,117 2,117