Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details) - USD ($) $ in Millions	Dec. 31, 2022	Dec. 31, 2021
Payables and Accruals [Abstract]
Accrued payroll and related costs	$ 497.3	$ 440.7
Accrued clinical expenses	295.0	295.8
Accrued sales-related costs	633.6	472.7
Income taxes payable	0.3	326.3
Amounts due to collaborators (see Note 3)	10.5	287.4
Other accrued expenses and liabilities	637.5	383.9
Accrued expenses and other current liabilities	$ 2,074.2	$ 2,206.8