Property, Plant, and Equipment (Tables)

12 Months Ended

Dec. 31, 2022

Property, Plant and Equipment [Abstract]

Schedule of property, plant and equipment

The estimated useful lives of property, plant, and equipment are as follows:

Building and improvements	10–50 years
Laboratory and other equipment	3–10 years
Furniture and fixtures	5 years

Property, plant, and equipment consists of the following:

	As of December 31,
(In millions)	2022		2021
Land	$	264.5	$	248.0
Building and improvements	2,270.0		2,088.5
Leasehold improvements	114.3		113.9
Construction in progress	980.5		767.7
Laboratory equipment	1,315.3		1,225.5
Computer equipment and software	337.4		291.5
Furniture, office equipment, and other	150.2		145.2
	5,432.2		4,880.3
Less, accumulated depreciation and amortization	(1,669.2)		(1,398.1)
	$	3,763.0	$	3,482.2