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Collaboration Agreements - Amounts Recognized in Statement of Operations with Bayer (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Disaggregation of Revenue [Line Items]        
Revenues $ 2,936.2 $ 3,452.8 $ 8,758.5 $ 11,120.0
Bayer | Outside United States | Collaboration revenue | Regeneron's share of profits in connection with commercialization of EYLEA outside the United States        
Disaggregation of Revenue [Line Items]        
Revenues 315.3 351.0 993.4 995.3
Bayer | Outside United States | Collaboration revenue | Reimbursement for manufacturing of ex-U.S. commercial supplies        
Disaggregation of Revenue [Line Items]        
Revenues 17.5 14.0 60.3 41.6
Bayer | Outside United States | Collaboration revenue | One-time payment in connection with change in Japan arrangement        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 0.0 21.9 0.0
Bayer | Outside United States | (R&D expense)/reduction of R&D expense | Reimbursement of R&D expenses        
Disaggregation of Revenue [Line Items]        
Revenues 11.8 14.5 32.7 35.2
Bayer | Outside United States | (R&D expense)/reduction of R&D expense | Regeneron's obligation for its share of Bayer research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues $ (4.7) $ (8.0) $ (22.4) $ (31.4)