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Collaboration, License, and Other Agreements - Amounts Recognized In Statement of Operations with Sanofi (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Disaggregation of Revenue [Line Items]        
Revenues $ 2,936.2 $ 3,452.8 $ 8,758.5 $ 11,120.0
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Regeneron's share of profits (losses) in connection with commercialization        
Disaggregation of Revenue [Line Items]        
Revenues 551.1 387.0 1,463.0 975.2
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Sales-based milestone earned        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 50.0 50.0 50.0
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Reimbursement for manufacturing of commercial supplies        
Disaggregation of Revenue [Line Items]        
Revenues 160.5 144.7 466.8 361.2
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Other        
Disaggregation of Revenue [Line Items]        
Revenues (0.2) 0.0 28.7 0.0
Sanofi Collaboration Agreement, Antibody | (R&D expense)/reduction of R&D expense | (Regeneron's obligation for its share of Sanofi R&D expenses)/reimbursements of R&D expenses, net        
Disaggregation of Revenue [Line Items]        
Revenues (4.3) 34.9 59.6 89.5
Sanofi Collaboration Agreement, Antibody | Selling, general and administrative expense | Reimbursement of commercialization-related expenses        
Disaggregation of Revenue [Line Items]        
Revenues 108.6 79.0 311.1 216.9
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Regeneron's share of profits (losses) in connection with commercialization | Outside United States        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 (3.0) 6.7 (12.6)
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Reimbursement for manufacturing of ex-U.S. commercial supplies        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 3.1 4.6 10.5
Sanofi Collaboration Agreement, Immuno-oncology | (R&D expense)/reduction of R&D expense | Reimbursement of R&D expenses        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 21.8 42.7 66.2
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Reimbursement of commercialization-related expenses        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 22.8 41.4 62.0
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Regeneron's obligation for its share of Sanofi commercial expenses        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 (9.4) (19.9) (28.0)
Sanofi Collaboration Agreement, Immuno-oncology | Cost of goods sold | Regeneron's obligation for Sanofi's share of Libtayo U.S. gross profits        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 (34.6) (70.1) (99.4)
Sanofi Collaboration Agreement, Immuno-oncology | Other operating income | Amounts recognized in connection with up-front payments received        
Disaggregation of Revenue [Line Items]        
Revenues $ 0.0 $ (47.7) $ 35.1 $ (4.1)