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Collaboration Agreements - Amounts Recognized in Statement of Operations with Bayer (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Disaggregation of Revenue [Line Items]        
Revenues $ 2,857.2 $ 5,138.5 $ 5,822.3 $ 7,667.2
Bayer | Outside United States | Collaboration revenue | Regeneron's share of profits in connection with commercialization of EYLEA outside the United States        
Disaggregation of Revenue [Line Items]        
Revenues 339.7 335.4 678.1 644.3
Bayer | Outside United States | Collaboration revenue | Reimbursement for manufacturing of ex-U.S. commercial supplies        
Disaggregation of Revenue [Line Items]        
Revenues 17.8 13.7 42.8 27.6
Bayer | Outside United States | Collaboration revenue | One-time payment in connection with change in Japan arrangement        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 0.0 21.9 0.0
Bayer | Outside United States | Research and development expense | Reimbursement of research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues 9.8 9.9 20.9 20.7
Bayer | Outside United States | Research and development expense | Regeneron's obligation for its share of Bayer research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues $ (6.9) $ (10.9) $ (17.7) $ (23.4)