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Collaboration, License, and Other Agreements - Amounts Recognized In Statement of Operations with Sanofi (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Disaggregation of Revenue [Line Items]        
Revenues $ 2,857.2 $ 5,138.5 $ 5,822.3 $ 7,667.2
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Regeneron's share of profits (losses) in connection with commercialization        
Disaggregation of Revenue [Line Items]        
Revenues 496.6 327.6 911.9 588.2
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Sales-based milestone earned        
Disaggregation of Revenue [Line Items]        
Revenues 0.0 0.0 50.0 0.0
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Reimbursement for manufacturing of commercial supplies        
Disaggregation of Revenue [Line Items]        
Revenues 145.5 110.9 306.3 216.5
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Other        
Disaggregation of Revenue [Line Items]        
Revenues 28.9 0.0 28.9 0.0
Sanofi Collaboration Agreement, Antibody | Research and development expense | Reimbursement of research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues 52.7 46.5 89.2 77.1
Sanofi Collaboration Agreement, Antibody | Research and development expense | Regeneron's obligation for its share of Sanofi research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues (15.6) (10.6) (25.3) (22.5)
Sanofi Collaboration Agreement, Antibody | Selling, general and administrative expense | Reimbursement of commercialization-related expenses        
Disaggregation of Revenue [Line Items]        
Revenues 110.8 78.3 202.5 137.9
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Regeneron's share of profits (losses) in connection with commercialization | Outside United States        
Disaggregation of Revenue [Line Items]        
Revenues 3.9 (3.5) 6.7 (9.6)
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Reimbursement for manufacturing of ex-U.S. commercial supplies        
Disaggregation of Revenue [Line Items]        
Revenues 2.6 2.7 4.6 7.4
Sanofi Collaboration Agreement, Immuno-oncology | Research and development expense | Reimbursement of research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues 21.2 22.5 42.7 44.4
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Reimbursement of commercialization-related expenses        
Disaggregation of Revenue [Line Items]        
Revenues 22.4 20.7 41.4 39.2
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Regeneron's obligation for its share of Sanofi commercial expenses        
Disaggregation of Revenue [Line Items]        
Revenues (10.7) (10.9) (19.9) (18.6)
Sanofi Collaboration Agreement, Immuno-oncology | Cost of goods sold | Regeneron's obligation for Sanofi's share of Libtayo U.S. gross profits        
Disaggregation of Revenue [Line Items]        
Revenues (37.8) (34.4) (70.1) (64.8)
Sanofi Collaboration Agreement, Immuno-oncology | Other operating income | Amounts recognized in connection with up-front payments received        
Disaggregation of Revenue [Line Items]        
Revenues $ 17.0 $ 20.7 $ 35.1 $ 43.6