Product Sales - Schedule of Net Product Sales (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Disaggregation of Revenue [Line Items]
Revenues	$ 2,857.2	$ 5,138.5	$ 5,822.3	$ 7,667.2
UNITED STATES
Disaggregation of Revenue [Line Items]
Revenues	1,754.4	4,137.8	3,393.0	5,862.1
UNITED STATES | EYLEA
Disaggregation of Revenue [Line Items]
Revenues	1,621.2	1,424.7	3,138.8	2,771.7
UNITED STATES | Libtayo
Disaggregation of Revenue [Line Items]
Revenues	90.9	78.0	169.8	147.1
UNITED STATES | Praluent
Disaggregation of Revenue [Line Items]
Revenues	31.2	41.9	64.8	85.2
UNITED STATES | REGEN-COV
Disaggregation of Revenue [Line Items]
Revenues	0.0	2,591.2	0.0	2,853.4
UNITED STATES | Evkeeza
Disaggregation of Revenue [Line Items]
Revenues	11.1	2.0	19.6	2.5
UNITED STATES | ARCALYST
Disaggregation of Revenue [Line Items]
Revenues	$ 0.0	$ 0.0	$ 0.0	$ 2.2