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Inventories
6 Months Ended
Jun. 30, 2022
Inventory Disclosure [Abstract]  
Inventories Inventories
Inventories consist of the following:
June 30,December 31,
(In millions)20222021
Raw materials$831.7 $721.9 
Work-in-process717.3 707.2 
Finished goods45.6 73.7 
Deferred costs623.9 448.5 
$2,218.5 $1,951.3 
Deferred costs represent the costs of product manufactured and shipped to the Company's collaborators for which recognition of revenue has been deferred. For the three and six months ended June 30, 2022, Cost of goods sold included inventory write-offs and reserves totaling $19.2 million and $66.6 million, respectively. For the three and six months ended June 30, 2021, Cost of goods sold included inventory write-offs and reserves totaling $139.9 million and $149.3 million, respectively.