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Collaboration, License, and Other Agreements - Alnylam (Details) - USD ($)
$ in Millions
Mar. 31, 2022
Dec. 31, 2021
Disaggregation of Revenue [Line Items]    
Accounts receivable, net $ 4,839.0 $ 6,036.5
Roche Collaboration Agreement    
Disaggregation of Revenue [Line Items]    
Accounts receivable, net 204.3 0.0
Accrued expenses and other current liabilities $ 0.0 $ 268.8