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Collaboration Agreements - Amounts Recognized in Statement of Operations with Bayer (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Disaggregation of Revenue [Line Items]    
Revenues $ 2,965.1 $ 2,528.7
Bayer | Outside United States | Collaboration revenue | Regeneron's share of profits in connection with commercialization of EYLEA outside the United States    
Disaggregation of Revenue [Line Items]    
Revenues 338.4 308.9
Bayer | Outside United States | Collaboration revenue | Reimbursement for manufacturing of commercial supplies    
Disaggregation of Revenue [Line Items]    
Revenues 25.0 13.9
Bayer | Outside United States | Collaboration revenue | One-time payment in connection with change in Japan arrangement    
Disaggregation of Revenue [Line Items]    
Revenues 21.9 0.0
Bayer | Outside United States | Research and development expense | Reimbursement of research and development expenses    
Disaggregation of Revenue [Line Items]    
Revenues 11.1 10.8
Bayer | Outside United States | Research and development expense | Regeneron's obligation for its share of Bayer research and development expenses    
Disaggregation of Revenue [Line Items]    
Revenues $ (10.8) $ (12.5)