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Inventories - Narrative (Details) - USD ($)
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Inventory [Line Items]        
Inventory reserves $ 510.0 $ 510.0 $ 136.4  
Inventory write-downs and reserves   $ 457.1 $ 39.2 $ 73.8
REGEN-COV        
Inventory [Line Items]        
Inventory write-downs and reserves $ 231.7