Property, Plant, and Equipment (Tables)

12 Months Ended

Dec. 31, 2021

Property, Plant and Equipment [Abstract]

Schedule of property, plant and equipment

The estimated useful lives of property, plant, and equipment are as follows:

Building and improvements	10–50 years
Laboratory and other equipment	3–10 years
Furniture and fixtures	5 years

Property, plant, and equipment consists of the following:

	As of December 31,
(In millions)	2021		2020
Land	$	248.0	$	241.2
Building and improvements	2,088.5		1,891.1
Leasehold improvements	113.9		100.5
Construction in progress	767.7		724.5
Laboratory equipment	1,225.5		1,038.6
Computer equipment and software	291.5		226.3
Furniture, office equipment, and other	145.2		130.5
	4,880.3		4,352.7
Less, accumulated depreciation and amortization	(1,398.1)		(1,131.1)
	$	3,482.2	$	3,221.6