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Collaboration, License, and Other Agreements - Amounts Recognized In Statement of Operations with Sanofi (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2021
Sep. 30, 2020
Sep. 30, 2021
Sep. 30, 2020
Disaggregation of Revenue [Line Items]        
Revenues $ 3,452.8 $ 2,294.0 $ 11,120.0 $ 6,074.2
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Regeneron's share of profits (losses) in connection with commercialization        
Disaggregation of Revenue [Line Items]        
Revenues 387.0 212.8 975.2 555.6
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Sales-based milestone earned        
Disaggregation of Revenue [Line Items]        
Revenues 50.0 50.0 50.0 50.0
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Reimbursement for manufacturing of commercial supplies        
Disaggregation of Revenue [Line Items]        
Revenues 144.7 94.3 361.2 275.0
Sanofi Collaboration Agreement, Antibody | Research and development expense | Reimbursement of research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues 45.2 45.5 122.3 174.4
Sanofi Collaboration Agreement, Antibody | Research and development expense | Regeneron's obligation for its share of Sanofi research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues (10.3) (17.5) (32.8) (59.1)
Sanofi Collaboration Agreement, Antibody | Selling, general and administrative expense | Reimbursement of commercialization-related expenses        
Disaggregation of Revenue [Line Items]        
Revenues 79.0 83.2 216.9 260.4
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Regeneron's share of profits (losses) in connection with commercialization | Outside United States        
Disaggregation of Revenue [Line Items]        
Revenues (3.0) (4.7) (12.6) (17.3)
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Reimbursement for manufacturing of commercial supplies        
Disaggregation of Revenue [Line Items]        
Revenues 3.1 0.9 10.5 6.0
Sanofi Collaboration Agreement, Immuno-oncology | Research and development expense | Reimbursement of research and development expenses        
Disaggregation of Revenue [Line Items]        
Revenues 21.8 49.8 66.2 136.7
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Reimbursement of commercialization-related expenses        
Disaggregation of Revenue [Line Items]        
Revenues 22.8 14.5 62.0 39.2
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Regeneron's obligation for its share of Sanofi commercial expenses        
Disaggregation of Revenue [Line Items]        
Revenues (9.4) (6.1) (28.0) (15.0)
Sanofi Collaboration Agreement, Immuno-oncology | Cost of goods sold | Regeneron's obligation for Sanofi's share of Libtayo U.S. gross profits        
Disaggregation of Revenue [Line Items]        
Revenues (34.6) (31.5) (99.4) (86.5)
Sanofi Collaboration Agreement, Immuno-oncology | Other operating income | Amounts recognized in connection with up-front payments received        
Disaggregation of Revenue [Line Items]        
Revenues $ (47.7) $ 20.0 $ (4.1) $ 57.0