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Collaboration, License, and Other Agreements - Amounts Recognized in Statement of Operations with Teva (Details) - Teva - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Reimbursement of research and development expenses | Research and development expense        
Disaggregation of Revenue [Line Items]        
Reduction of Research and development expense $ 11.7 $ 31.0 $ 31.5 $ 56.2
Amounts recognized in connection with up-front and development milestone payments received | Other operating income        
Disaggregation of Revenue [Line Items]        
Other operating income $ 7.2 $ 20.7 $ 19.4 $ 37.3