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Collaboration Agreements - Amounts Recognized in Statement of Operations with Bayer (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Disaggregation of Revenue [Line Items]    
Revenues $ 2,528.7 $ 1,828.2
Bayer | Outside United States | Collaboration revenue | Regeneron's net profit in connection with commercialization of EYLEA outside the United States    
Disaggregation of Revenue [Line Items]    
Revenues 308.9 253.8
Bayer | Outside United States | Collaboration revenue | Reimbursement for manufacturing of commercial supplies    
Disaggregation of Revenue [Line Items]    
Revenues 13.9 27.6
Bayer | Outside United States | Research and development expense | Reimbursement of research and development expenses    
Disaggregation of Revenue [Line Items]    
Revenues 10.8 12.0
Bayer | Outside United States | Research and development expense | Regeneron's obligation for its share of Bayer research and development expenses    
Disaggregation of Revenue [Line Items]    
Revenues $ (12.5) $ (8.1)