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Collaboration, License, and Other Agreements - Amounts Recognized In Statement of Operations with Sanofi (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Disaggregation of Revenue [Line Items]    
Revenues $ 2,528.7 $ 1,828.2
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Regeneron's share of profits in connection with commercialization    
Disaggregation of Revenue [Line Items]    
Revenues 260.6 170.9
Sanofi Collaboration Agreement, Antibody | Collaboration revenue | Reimbursement for manufacturing of commercial supplies    
Disaggregation of Revenue [Line Items]    
Revenues 105.6 80.1
Sanofi Collaboration Agreement, Antibody | Research and development expense | Reimbursement of research and development expenses    
Disaggregation of Revenue [Line Items]    
Revenues 30.1 77.6
Sanofi Collaboration Agreement, Antibody | Research and development expense | Regeneron's obligation for its share of Sanofi research and development expenses    
Disaggregation of Revenue [Line Items]    
Revenues (11.9) (16.7)
Sanofi Collaboration Agreement, Antibody | Selling, general and administrative expense | Reimbursement of commercialization-related expenses    
Disaggregation of Revenue [Line Items]    
Revenues 60.4 91.2
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Regeneron's share of profits in connection with commercialization | Outside United States    
Disaggregation of Revenue [Line Items]    
Revenues (6.1) (6.2)
Sanofi Collaboration Agreement, Immuno-oncology | Collaboration revenue | Reimbursement for manufacturing of commercial supplies    
Disaggregation of Revenue [Line Items]    
Revenues 4.7 2.1
Sanofi Collaboration Agreement, Immuno-oncology | Research and development expense | Reimbursement of research and development expenses    
Disaggregation of Revenue [Line Items]    
Revenues 21.9 39.9
Sanofi Collaboration Agreement, Immuno-oncology | Selling, general and administrative expense | Reimbursement of commercialization-related expenses    
Disaggregation of Revenue [Line Items]    
Revenues 18.5 10.4
Sanofi Collaboration Agreement, Immuno-oncology | Cost of goods sold | Regeneron's obligation for Sanofi's share of Libtayo U.S. gross profits    
Disaggregation of Revenue [Line Items]    
Revenues (30.4) (26.8)
Sanofi Collaboration Agreement, Immuno-oncology | Other operating income | Amounts recognized in connection with up-front payments received    
Disaggregation of Revenue [Line Items]    
Revenues $ 22.9 $ 16.5