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Stockholders' Equity - Narrative (Details)
1 Months Ended 12 Months Ended
Dec. 31, 2020
USD ($)
$ / shares
shares
May 31, 2020
USD ($)
shares
Dec. 31, 2020
USD ($)
vote
$ / shares
shares
Dec. 31, 2019
USD ($)
$ / shares
shares
Dec. 31, 2007
shares
Jan. 31, 2021
USD ($)
Nov. 30, 2019
USD ($)
Class of Stock [Line Items]              
Preferred Stock, shares authorized (in shares) 30,000,000   30,000,000 30,000,000      
Sanofi              
Class of Stock [Line Items]              
Cost of stock repurchased | $   $ 5,000,000,000          
Number of shares sold (in shares)   13,014,646          
Treasury stock, shares acquired (in shares)   9,806,805          
Common Stock, shares outstanding (in shares)   400,000          
Sanofi              
Class of Stock [Line Items]              
Number of shares of common stock purchased (in shares)         12,000,000    
Maximum percentage of outstanding shares that may be acquired, under 'standstill' provisions 30.00%   30.00%        
Percentage of outstanding shares or voting rights under amended investor agreement 20.00%   20.00%        
Bayer              
Class of Stock [Line Items]              
Maximum percentage of outstanding shares that may be acquired, under 'standstill' provisions 20.00%   20.00%        
Teva              
Class of Stock [Line Items]              
Maximum percentage of outstanding shares that may be acquired, under 'standstill' provisions 5.00%   5.00%        
2019 Share Repurchase Program              
Class of Stock [Line Items]              
Stock repurchase program, authorized amount | $             $ 1,000,000,000.0
Cost of stock repurchased | $ $ 1,000,000,000.0   $ 746,000,000.0 $ 254,000,000.0      
Treasury stock, shares acquired (in shares)     1,605,582 722,596      
2021 Share Repurchase Program | Subsequent Event              
Class of Stock [Line Items]              
Stock repurchase program, authorized amount | $           $ 1,500,000,000  
Class A Stock              
Class of Stock [Line Items]              
Common Stock, shares authorized (in shares) 40,000,000   40,000,000 40,000,000      
Common Stock, par value (in dollars per share) | $ / shares $ 0.001   $ 0.001 $ 0.001      
Number of votes per share | vote     10        
Common Stock, shares outstanding (in shares) 1,848,970   1,848,970 1,848,970      
Common Stock              
Class of Stock [Line Items]              
Common Stock, shares authorized (in shares) 320,000,000   320,000,000 320,000,000      
Common Stock, par value (in dollars per share) | $ / shares $ 0.001   $ 0.001 $ 0.001      
Number of votes per share | vote     1