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Product Sales
 12 Months Ended
Dec. 31, 2020
Revenues [Abstract]  
Product Sales Product Sales
Net product sales consist of the following:
Year Ended December 31,
Net Product Sales in the United States202020192018
EYLEA$4,947.2 $4,644.2 $4,076.7 
Libtayo270.7 175.7 14.8 
Praluent150.9 **
REGEN-COV185.7 — — 
ARCALYST13.1 14.5 14.7 
$5,567.6 $4,834.4 $4,106.2 
* Effective April 1, 2020, the Company is solely responsible for the development and commercialization of Praluent in the United States and records net product sales of Praluent in the United States. See Note 3 for further details.
The Company had product sales to certain customers that accounted for more than 10% of total gross product revenue for each of the years ended December 31, 2020, 2019, and 2018. Sales to each of these customers as a percentage of the Company's total gross product revenue are as follows:
Year Ended December 31,
202020192018
Besse Medical, a subsidiary of AmerisourceBergen Corporation
51 %57 %56 %
McKesson Corporation32 %33 %36 %
Revenue from product sales is recorded net of applicable provisions for rebates, chargebacks, and discounts, distribution-related fees, and other sales-related deductions. Accruals for chargebacks and discounts are recorded as a direct reduction to accounts receivable. Accruals for rebates, distribution-related fees, and other sales-related deductions are recorded within accrued liabilities.
The following table summarizes the provisions, and credits/payments, for sales-related deductions for the years ended December 31, 2020, 2019, and 2018.
Rebates, Chargebacks, and DiscountsDistribution-
Related Fees		Other Sales-
Related Deductions		Total
Balance as of December 31, 2017$29.9 $34.1 $21.3 $85.3 
Provisions
223.4 211.0 44.5 478.9 
Credits/payments(212.2)(203.1)(57.5)(472.8)
Balance as of December 31, 201841.1 42.0 8.3 91.4 
Provisions
423.2 242.9 61.8 727.9 
Credits/payments(384.0)(238.5)(40.7)(663.2)
Balance as of December 31, 201980.3 46.4 29.4 156.1 
Provisions
762.9 279.9 94.1 1,136.9 
Credits/payments(641.0)(249.1)(78.7)(968.8)
Balance as of December 31, 2020$202.2 $77.2 $44.8 $324.2