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Property, Plant, and Equipment (Tables)
12 Months Ended
Dec. 31, 2020
Property, Plant and Equipment [Abstract]  
Schedule of property, plant and equipment The estimated useful lives of property, plant, and equipment are as follows:
Building and improvements
10–50 years
Laboratory and other equipment
3–10 years
Furniture and fixtures
5 years
Property, plant, and equipment consists of the following:
As of December 31,
20202019
Land$241.2 $230.8 
Building and improvements1,891.1 1,683.4 
Leasehold improvements100.5 97.6 
Construction in progress724.5 644.8 
Laboratory equipment1,038.6 850.7 
Computer equipment and software226.3 183.7 
Furniture, office equipment, and other
130.5 121.8 
4,352.7 3,812.8 
Less, accumulated depreciation and amortization
(1,131.1)(922.4)
$3,221.6 $2,890.4