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Stockholders' Equity - Narrative (Details) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
May 31, 2020
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Sep. 30, 2019
Mar. 31, 2019
Sep. 30, 2020
Nov. 30, 2019
Class of Stock [Line Items]                
Treasury stock, shares acquired (in shares) 9,806,805              
Cost of treasury stock received $ 5,000,000,000 $ 100,400,000 $ 5,071,800,000 $ 336,000,000.0 $ 48,700,000 $ 54,000,000.0    
Sanofi Collaboration Agreement, Immuno-oncology                
Class of Stock [Line Items]                
Maximum shares the collaborator could sell (in shares)   279,766         279,766  
Sanofi                
Class of Stock [Line Items]                
Number of shares sold (in shares) 13,014,646              
Common Stock, shares outstanding (in shares) 400,000              
Share Repurchase Program                
Class of Stock [Line Items]                
Share repurchase program, authorized amount               $ 1,000,000,000.0
Remaining authorized repurchase amount   $ 372,700,000         $ 372,700,000  
Treasury stock, shares acquired (in shares)   179,824         898,991  
Cost of treasury stock received   $ 100,400,000         $ 373,300,000