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Collaboration, License, and Other Agreements - Sanofi, Antibody Narrative (Details) - USD ($)
3 Months Ended 6 Months Ended
Apr. 01, 2020
Jun. 30, 2020
Jun. 30, 2020
Sanofi Collaboration Agreement, Antibody      
Disaggregation of Revenue [Line Items]      
Percentage of Trial Costs borne by collaborating party     80.00%
Percentage of Trial Costs borne by entity     20.00%
Maximum amount of sales milestone payments if total sales achieve specific levels     $ 250,000,000.0
Levels of twelve month sales at which sales milestone payments would be received     $ 1,000,000,000.0
Period for achieving sales target for milestone payment, rolling basis     12 months
Praluent Agreement      
Disaggregation of Revenue [Line Items]      
Royalty percentage to be received on net product sales outside of the United States 5.00%    
Percentage of damages company is responsible for   50.00%  
Sanofi | Praluent Agreement      
Disaggregation of Revenue [Line Items]      
Percentage of royalty payment that can be used to offset litigation proceedings   50.00%