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Interim Financial Statements - Schedule of Statements of Operations Data (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues $ 1,952.0 $ 1,577.8 $ 3,780.2 $ 2,950.4
Research and development 722.0 885.5 1,305.9 1,371.6
Selling, general, and administrative 348.3 294.6 715.6 585.7
Other operating (income) expense, net (50.2) (63.7) (90.6) (120.4)
Total operating expenses 1,295.6 1,262.2 2,423.7 2,154.8
Collaboration and contract manufacturing        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Cost of goods sold 173.0 78.8 311.5 180.0
Sanofi | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 269.1 75.8 516.0 57.8
Bayer | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 244.2 277.2 525.6 541.2
Other | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues $ 211.8 19.5 $ 275.0 41.7
As Previously Reported        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   1,933.7   3,645.5
Research and development   1,048.3   1,690.1
Selling, general, and administrative   417.3   828.1
Other operating (income) expense, net   0.0   0.0
Total operating expenses   1,618.1   2,849.9
As Previously Reported | Collaboration and contract manufacturing        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Cost of goods sold   85.5   193.8
As Previously Reported | Sanofi | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   349.1   595.5
As Previously Reported | Bayer | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   289.0   565.2
As Previously Reported | Other | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   90.3   175.1
Adjustments        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   (355.9)   (695.1)
Research and development   (162.8)   (318.5)
Selling, general, and administrative   (122.7)   (242.4)
Other operating (income) expense, net   (63.7)   (120.4)
Total operating expenses   (355.9)   (695.1)
Adjustments | Collaboration and contract manufacturing        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Cost of goods sold   (6.7)   (13.8)
Adjustments | Sanofi | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   (273.3)   (537.7)
Adjustments | Bayer | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   (11.8)   (24.0)
Adjustments | Other | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues   $ (70.8)   $ (133.4)