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Collaboration Agreements - Sanofi, Antibody Narrative (Details) - USD ($)
3 Months Ended
Apr. 01, 2020
Mar. 31, 2020
Sanofi Collaboration Agreement, Antibody    
Disaggregation of Revenue [Line Items]    
Percentage of Trial Costs borne by collaborating party   80.00%
Percentage of Trial Costs borne by entity   20.00%
Maximum amount of sales milestone payments if total sales achieve specific levels   $ 250,000,000.0
Levels of twelve month sales at which sales milestone payments would be received   $ 1,000,000,000.0
Period for achieving sales target for milestone payment, rolling basis   12 months
Praluent Agreement    
Disaggregation of Revenue [Line Items]    
Percentage of damages company is responsible for   50.00%
Subsequent Event | Praluent Agreement    
Disaggregation of Revenue [Line Items]    
Royalty percentage to be received on net product sales outside of the United States 5.00%  
Sanofi | Praluent Agreement    
Disaggregation of Revenue [Line Items]    
Percentage of royalty payment that can be used to offset litigation proceedings   50.00%