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Statement of Cash Flows - Narrative (Details) - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Condensed Cash Flow Statements, Captions [Line Items]      
Accrued capital expenditures $ 133,700,000 $ 54,500,000 $ 41,800,000
Treasury stock, shares acquired (in shares) 722,596    
Cost of treasury stock shares received $ 254,000,000.0    
Capital lease obligations incurred $ 0 $ 0 $ 201,200,000
Sanofi Collaboration Agreement, Immuno-oncology      
Condensed Cash Flow Statements, Captions [Line Items]      
Treasury stock, shares acquired (in shares) 210,733 215,387  
Cost of treasury stock shares received $ 73,300,000 $ 75,800,000